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Biliary Cryptosporidiosis in HIV-infected
People After the Waterborne Outbreak of
Cryptosporidiosis in Milwaukee
Vakil, Nimish; Schwartz, Steven;
Buggy, Brian, P.; et al.
New England Journal of Medicine (01/04/96) Vol
334, No.1, P. 19
In March 1993, a cryptosporidiosis outbreak
occurred in Milwaukee, Wisc., when the municipal
water supply was contaminated with cryptosporidium.
Vakil et al. analyzed the clinical condition, CD4
cell count, and survival rate of a group of 82
HIV-infected patients who developed
cryptosporidiosis during the outbreak. The authors
report an increase, after the period of
contamination, in the number of HIV-infected
patients with cryptosporidiosis. One year after the
outbreak, 17 percent of the patients with biliary
symptoms and 52 percent of the patients without
biliary symptoms had survived. Of the patients with
biliary symptoms, 88 percent had CD4 counts less
than 50, compared to 63 percent among those without
biliary symptoms. The researchers concluded that
HIV-infected patients with CD4 counts less than 50
per cubic millimeter who are exposed to
cryptosporidium are at increased risk for biliary
symptoms and for death within a year after that
infection.
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The CDC National Center for HIV, STD,
and TB Prevention makes this information available as a
public service only. Providing this information does not
constitute endorsement by the CDC. Reproduction of this text
is encouraged; however, copies may not be sold, and the CDC
National AIDS Clearinghouse should be cited as the source.
Copyright 1996, Information, Inc., Bethesda, MD
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